发明名称 Method for the identification of epitopes related to immunogenicity in biopharmaceuticals
摘要 The present invention relates to a method for identifying peptides involved in immunogenicity comprising the steps of a) providing cells expressing antigen presenting receptors (APR) in a number providing 0.1 to 5 ug of APR molecules, b) contacting the cells from (a) with a source of immunogenic peptides, c) isolating APR molecule-immunogenic pep tide complexes from the cells, d) eluting the associated peptides from the APR molecules, e) identifying the immunogenic peptides, and f) verifying the identified immunogenic peptides as epitopes.
申请公布号 US2006251664(A1) 申请公布日期 2006.11.09
申请号 US20060404253 申请日期 2006.04.13
申请人 KROPSHOFER HARALD;VOGT ANNE 发明人 KROPSHOFER HARALD;VOGT ANNE
分类号 G01N33/567;A61K39/00 主分类号 G01N33/567
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