METHODS AND COMPOSITIONS FOR COMBINATORAL-BASED PRODUCTION OF MULTIVALENT RECOMBINANT ANTIGENS
摘要
The present invention provides methods and compositions for rapidly producing multivalent recombinant vaccines using filamentous fungal heterokaryons. The present invention relies on the use of filamentous fungal heterokaryons that are generated from combinations of two or more parent strains into which recombinant DNA molecules encoding variants of antigens derived from pathogenic organisms have been introduced. The resulting vaccines are multivalent.
申请公布号
WO2006044796(A3)
申请公布日期
2006.11.09
申请号
WO2005US37249
申请日期
2005.10.17
申请人
NEUGENESIS CORPORATION;STUART, DORSEY, W.;CAMBARERI, EDWARD, B.