发明名称 HUMAN MICRORNAS AND METHODS FOR INHIBITING SAME
摘要 <p>The invention relates to isolated DNA or RNA molecules comprising at least ten contiguous bases having a sequence in a microRNA shown in SEQ ID NOs: 1-94; 281-374; 467- 481 ; 497-522; or 549, except that up to thirty percent of the bases may be wobble bases, and up to 10% of the contiguous bases may be non-complementary. The invention further relates to modified single stranded microRNA molecules, isolated single stranded anti-microRNA molecules and isolated microRNP molecules. In another embodiment, the invention relates to a method for inhibiting microRNP activity in a cell.</p>
申请公布号 CA2605701(A1) 申请公布日期 2006.11.09
申请号 CA20062605701 申请日期 2006.05.01
申请人 ROCKEFELLER UNIVERSITY 发明人 TUSCHL, THOMAS;LANDGRAF, PABLO
分类号 C12Q1/68 主分类号 C12Q1/68
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