NITROGENOUS FUSED HETEROAROMATIC RING DERIVATIVE

摘要

The invention provides a compound or its pharmaceutically-acceptable salt of formula (I):
wherein A 1 is a hydrogen, etc.; j and k are 0 or 1;
is a double bond, etc.;
is a double bond, etc.;
one of W 1 and W 2 is E-O-W, etc., and the other is a hydrogen atom, etc.; E is a divalent group derived from a benzene ring, etc., by removing two hydrogen atoms therefrom; W is a group of formula (II-1):
which has a histamine-H3 receptor antagonistic effect or a histamine-H3 receptor inverse-agonistic effect and is useful for prevention or remedy of metabolic system diseases, circulatory system diseases or nervous system diseases.