发明名称 |
THERAPEUTIC METHODS EMPLOYING NITRIC OXIDE PRECURSORS |
摘要 |
Isolated polynucleotide molecules and peptides encoded by these molecules are used in the analysis of human carbamyl phosphate synthetase I phenotypes, as well as in diagnostic and therapeutic applications, relating to a human carbamyl phosphate synthetase I polymorphism. By analyzing genomic DNA or amplified genomic DNA, or amplified cDNA derived from mRNA, it is possible to type a human carbamyl phosphate synthetase I with regard to the human carbamyl phosphate synthetase I polymorphism, for example, in the context of diagnosing and treating hepatic veno-occlusive disease (HVOD) associated with bone marrow transplants. |
申请公布号 |
EP1718289(A2) |
申请公布日期 |
2006.11.08 |
申请号 |
EP20050723789 |
申请日期 |
2005.02.24 |
申请人 |
VANDERBILT UNIVERSITY |
发明人 |
SUMMAR, MARSHALL, L.;CHRISTMAN, BRIAN;BARR, FREDERICK, E. |
分类号 |
A61K31/198;A61K38/00;C12N9/00 |
主分类号 |
A61K31/198 |
代理机构 |
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代理人 |
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地址 |
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