MATERIAL FOR BUFFERED RESORBABLE INTERNAL FIXATION DEVICES AND METHOD FOR MAKING SAME

摘要

A bioerodible implantable material, comprising a bioerodible polymer that produces acidic products upon hydrolytic degradation, and a buffering compound that buffers the acidic products and maintains the loca l pH within a desired range. The buffer compound acts to reduce the inflammatory foreign body response generated by the acidic produc ts and reduces the sterile abscess condition that occurs at the site of the bioerodible implant materials of the prior art. Materials ma de according to the invention may be used for internal fixation devices (IFDs) for bone repair.