摘要 |
A compound of the following general formula or its salt or a hydrate thereof exhibits excellent hepatocyte growth factor receptor (HGFR) inhibiting activity and provides a compound having antitumor activity, vascularization inhibiting activity or cancer metastasis inhibiting activity or its salt or a hydrate thereof. (wherein R1 represents a C1-C6 alkyl, etc.; each of R2 and R3 represents a hydrogen atom; R4, R 5, R6 and R7 may be identical with or different from each other and each represent a hydrogen atom, a halogen atom, a C1-C6 alkyl, etc.; R8 represents a hydrogen atom, etc.; R9b represents a 3 to 10-membered nonaromatic heterocyclic group, etc.; V1 represents an oxygen atom, etc.; V2 represents an oxygen atom or a sulfur atom; W represents a group of the formula -CH2-, etc.; X represents a group of the formula -CH=, a nitrogen atom, etc.; and Y represents an oxygen atom, etc.).
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