发明名称 NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE(2)
摘要 A compound of the following general formula or its salt or a hydrate thereof exhibits excellent hepatocyte growth factor receptor (HGFR) inhibiting activity and provides a compound having antitumor activity, vascularization inhibiting activity or cancer metastasis inhibiting activity or its salt or a hydrate thereof. (wherein R1 represents a C1-C6 alkyl, etc.; each of R2 and R3 represents a hydrogen atom; R4, R 5, R6 and R7 may be identical with or different from each other and each represent a hydrogen atom, a halogen atom, a C1-C6 alkyl, etc.; R8 represents a hydrogen atom, etc.; R9b represents a 3 to 10-membered nonaromatic heterocyclic group, etc.; V1 represents an oxygen atom, etc.; V2 represents an oxygen atom or a sulfur atom; W represents a group of the formula -CH2-, etc.; X represents a group of the formula -CH=, a nitrogen atom, etc.; and Y represents an oxygen atom, etc.).
申请公布号 KR20060113991(A) 申请公布日期 2006.11.03
申请号 KR20067013907 申请日期 2006.07.11
申请人 EISAI CO., LTD. 发明人 MATSUSHIMA TOMOHIRO;TAKAHASHI KEIKO;FUNASAKA SETSUO;OBAISHI HIROSHI
分类号 C07D213/75;A61K31/44;A61K31/4409;A61K31/4427;A61K31/4439;A61K31/444;A61K31/4545;A61K31/496;A61K31/505;A61K31/506;A61K31/5377;A61K31/551;A61P1/18;A61P9/00;A61P11/00;A61P13/08;A61P13/12;A61P15/00;A61P25/00;A61P35/00;A61P35/04;A61P43/00;C07D213/73;C07D239/46;C07D239/47;C07D239/48;C07D401/12;C07D401/14;C07D403/12;C07D407/12;C07D409/12;C07D413/12;C07D487/08 主分类号 C07D213/75
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