| 摘要 |
The present invention relates to a method for the prevention, delay the onset and treatment of atherosclerosis which method comprises administering to a warm-blooded animal, in need thereof, a therapeutically effective amount of a renin inhibitor, or a pharmaceutically acceptable salt thereof, alone or in combination with at least one therapeutic agent selected from the group consisting of: (1) an ACE inhibitor, or a pharmaceutically acceptable salt thereof; (2) an angiotensin II receptor blocker, or a pharmaceutically acceptable salt thereof; (3) a diuretic, or a pharmaceutically acceptable salt thereof; (4) a calcium channel blocker (CCB), or a pharmaceutically acceptable salt thereof; (5) a beta-blocker, or a pharmaceutically acceptable salt thereof; (6) a platelet aggregation inhibitor, or a pharmaceutically acceptable salt thereof; (7) a cholesterol absorption modulator, or a pharmaceutically acceptable salt thereof; (8) a HMG-Co-A reductase inhibitor, or a pharmaceutically acceptable salt thereof; and (9) a high density lipoprotein (HDL) increasing compound, or a pharmaceutically acceptable salt thereof. |
