发明名称 |
LOW-CALCEMIC 16,23-DIENE 25-OXIME ANALOGS OF 1A ,25-DIHYDROXY VITAMIN D3 |
摘要 |
The present invention provides novel 16,23-diene 25-oxime ether analogs of 1,25-dihydroxy vitamin D3, compositions comprising these compounds and methods of using these compounds as inhibitors of CYP24. In particular, the novel compound of the invention are useful for treating diseases which benefit from a modulation of the levels of 1,25-dihydroxy vitamin D3, for example, cell-proliferative disorders. |
申请公布号 |
CA2605815(A1) |
申请公布日期 |
2006.11.02 |
申请号 |
CA20062605815 |
申请日期 |
2006.04.25 |
申请人 |
CYTOCHROMA INC.;JOHN HOPKINS UNIVERSITY |
发明人 |
POSNER, GARY H.;SAHA, UTTAM;KAHRAMAN, MEHMET |
分类号 |
C07C401/00;A61K31/59 |
主分类号 |
C07C401/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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