摘要 |
A compound corresponding to general formula (I): in which R<SUB>1 </SUB>represents a phenyl or naphthalenyl group optionally substituted with one or more halogen atoms or hydroxyl, cyano, nitro, (C<SUB>1</SUB>-C<SUB>3</SUB>) alkyl, (C<SUB>1</SUB>-C<SUB>3</SUB>) alkoxy, trifluoromethyl, trifluoromethoxy, benzyloxy, (C<SUB>3</SUB>-C<SUB>6</SUB>)cycloalkyl-O- or (C<SUB>3</SUB>-C<SUB>6</SUB>)cycloalkyl(C<SUB>1</SUB>-C<SUB>3</SUB>)alkoxy groups; R<SUB>2 </SUB>represents either a group of general formula CHR<SUB>3</SUB>CONHR<SUB>4 </SUB>in which R<SUB>3 </SUB>represents a hydrogen atom or a methyl group and R<SUB>4 </SUB>represents a hydrogen atom or a (C<SUB>1</SUB>-C<SUB>3</SUB>)alkyl, (C<SUB>3</SUB>-C<SUB>5</SUB>) cycloalkyl or (pyridin-4-yl)methyl group; or a 2,2,2-trifluoroethyl group; or an (imidazol-2-yl)methyl group; or a (benzimidazol-2-yl)methyl group; or a phenyl group optionally substituted with one or more halogen atoms or cyano, nitro, (C<SUB>1</SUB>-C<SUB>3</SUB>)alkyl, (C<SUB>1</SUB>-C<SUB>3</SUB>)alkoxy, trifluoromethyl or trifluoromethoxy groups; and n represents a number ranging from 1 to 3; in the form of a base, of an addition salt with an acid, of a hydrate or of a solvate. Also disclosed and claimed are the pharmaceutical compositions derived therefrom and their therapeutic use in treating a wide variety of diseases.
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