发明名称 |
Chromen-4-one inhibitors of anti-apoptotic Bcl-2 family members and the uses thereof |
摘要 |
The invention relates to small molecules which function as inhibitors of anti-apoptotic Bcl-2 family member proteins (e.g., Bcl-2 and Bcl-xL). The invention also relates to the use of these compounds for inducing apoptotic cell death and sensitizing cells to the induction of apoptotic cell death.
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申请公布号 |
US2006247305(A1) |
申请公布日期 |
2006.11.02 |
申请号 |
US20060373898 |
申请日期 |
2006.03.13 |
申请人 |
REGENTS OF THE UNIVERSITY OF MICHIGAN |
发明人 |
WANG SHAOMENG;DING KE;TANG GUOZHI;NIKOLOVSKA-COLESKA ZANETA;WANG RENXIO;YANG CHAO-YIE |
分类号 |
A61K31/353;C07D405/14 |
主分类号 |
A61K31/353 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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