发明名称 |
SUBSTITUTED 1H-PYRROLO[3,2-B, 3,2-C, AND 2,3-C]PYRIDINE-2-CARBOXAMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE Iepsilon |
摘要 |
The present invention discloses and claims substituted 1H-pyrrolo[3,2- b]pyridine-2-carboxamides, 1H-pyrrolo[3,2-c]pyridine-2-carboxamides and 1H-pyrrolo[2,3-c]pyridine-2-carboxamides (compounds of formula (I)) as inhibitors of human casein kinase I Epsilon, and methods of using said compounds of formula (I) for treating central nervous system diseases and disorders including mood disorders and sleep disorders. Pharmaceutical compositions comprising compounds of formula (I) and methods for the preparation of compounds of formula (I) are also disclosed and claimed.
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申请公布号 |
KR20060113754(A) |
申请公布日期 |
2006.11.02 |
申请号 |
KR20067013455 |
申请日期 |
2006.07.04 |
申请人 |
AVENTIS PHARMACEUTICALS, INC. |
发明人 |
METZ WILLIAM A.;HALLEY FRANK;DUTRUC ROSSET GILLES;CHOI SLEDESKI YONG MI;POLI GREGORY B.;FINK DAVID M.;DOERFLINGER GILLES;HUANG BAO GUO;GELORMINI ANN MARIE;GAMBOA JUAN A.;GIOVANNI ANDREW;ROEHR JOACHIM E.;TSAY JOSEPH T.;CAMACHO FERNANDO;HURST WILLIAM J.;HARNISH STEPHEN W.;CHIANG YULIN |
分类号 |
C07D471/04;A61K31/437 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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