METHODS FOR REDUCING THE PERCENTAGE OF ABNORMAL GAMETES
摘要
<p>The invention relates to methods of enriching a sperm sample for euploid sperm comprising obtaining a sperm sample from a mammalian male; contacting the sperm cells with a detectable DNA-interacting agent that imparts a sperm cell with a signal intensity proportional to the amount of DNA present in the sperm cell; and separating those sperm cells that have a signal intensity indicative of euploid sperm from those that have a signal intensity indicative of aneuploid sperm.</p>
