发明名称 |
A HYDROXAMIC ACID DERIVATIVE AND THE PREPARATION METHOD THEREOF |
摘要 |
Provided are a hydroxamic acid derivative which shows an antioxidizing effect and a collagen biosynthesis enhancing effect, its preparation method, and a skin preparation composition for external use containing the derivative. The hydroxamic acid derivative is represented by the formula 1, wherein R1 and R2 is a C1-C10 alkyl group; R3 is -(CH)n-; n is 0 or 1; and R4 is H or a methyl group. The method comprises the steps of reacting a 3,4-dialkoxybenzoic acid and methyl 4-aminobenzoate or methyl 4-aminophenyl acetate to prepare a benzamide compound; hydrolyzing a methyl ester group of the benzamide compound to prepare an acid; and reacting the acid with hydroxylamineÀHCl salt or N-methyl hydroxylamineÀHCl salt to prepare the hydroxamic acid derivative of the formula 1.
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申请公布号 |
KR20060113110(A) |
申请公布日期 |
2006.11.02 |
申请号 |
KR20050035986 |
申请日期 |
2005.04.29 |
申请人 |
AMOREPACIFIC CORPORATION |
发明人 |
RHO, HO SIK;BAEK, HEUNG SOO;LEE, JEONG A;PARK, CHANG MAN;KIM, DUCK HEE;CHANG, IH SEOP;LEE, OK SUB |
分类号 |
C07C239/18 |
主分类号 |
C07C239/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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