发明名称 |
Method for down-regulating gene expression in fungi |
摘要 |
The present invention concerns methods for controlling fungus infestation via dsRNA mediated gene silencing, whereby the intact fungus cell(s) are contacted with a double-stranded RNA from outside the fungal cell(s) and whereby the double-stranded RNA is taken up by the intact fungal cell(s). In one particular embodiment, the methods of the invention are used to alleviate plants from fungus pests. Alternatively, the methods are used for treating and/or preventing fungal infestation on a substrate or a subject in need of such treatment and/or prevention. Suitable fungal target genes and fragments thereof, dsRNA constructs, recombinant constructs and compositions are disclosed.
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申请公布号 |
US2006247197(A1) |
申请公布日期 |
2006.11.02 |
申请号 |
US20060396926 |
申请日期 |
2006.04.03 |
申请人 |
VAN DE CRAEN MARC;GOH PHUAY-YEE;LOGGHE MARC G;KHU YEE-LING;MORTIER KATHERINE;BOGAERT THIERRY A O |
发明人 |
VAN DE CRAEN MARC;GOH PHUAY-YEE;LOGGHE MARC G.;KHU YEE-LING;MORTIER KATHERINE;BOGAERT THIERRY A.O. |
分类号 |
A61K48/00;A01N43/04;C12N15/74 |
主分类号 |
A61K48/00 |
代理机构 |
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地址 |
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