Uses of cationic salts for polynucleotide synthesis

摘要

Are disclosed Inkjet printhead solvents and methods of forming an addressable nucleotide array, said method comprising
providing a first nucleotide compound selected from a nucleotide, an oligonucleotide, and a polynucleotide, wherein the first nucleotide compound is dissolved in a first solution including a first solvent, wherein the first solvent comprising an organic salt, wherein the organic salt comprises a substituted heterocyclic organic cation and an anion, wherein the first solution has a viscosity of about 5 to 20 cP and a surface tension of about 25 to 45 mN/m at a temperature of about 30 to 40°C;
disposing the first solution onto a first position on a substrate, wherein a structure is disposed in the first position, wherein the structure has a second nucleotide compound disposed thereon, wherein the second nucleotide compound is selected from a nucleotide, an oligonucleotide, and a polynucleotide; and disposing a second solution on the first position of the substrate, wherein the second solution includes an activator, wherein the activator initiates the formation of a third nucleotide including the first nucleotide compound and the second nucleotide compound.