| 摘要 |
PROBLEM TO BE SOLVED: To obtain a composition for medicine quickly disintegrating in the oral cavity, which has excellent disintegration in the oral cavity and high hardness and is especially applicable also to a pharmacodynamic component unstable to water. SOLUTION: The composition for medicine comprises lactose and powder cellulose exhibits high hardness without prolonging a disintegration time in the oral cavity. The composition for medicine increases hardness without prolonging a disintegration time in the oral cavity by including further a disintegrator. The composition for medicine comprising magnesium aluminometasilicate and one or more kinds selected from silicic acid and silicates except magnesium aluminometasilicate exhibits high hardness without prolonging a disintegration time in the oral cavity. The composition for medicine is produced by a general industrial production method without requiring a specific pharmaceutical manufacturing technology. COPYRIGHT: (C)2007,JPO&INPIT
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