| 发明名称 |
Macrocyclic compounds useful as pharmaceuticals |
| 摘要 |
The present invention provides compounds having formula (I): and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of various disorders including inflammatory or autoimmune disorders, and disorders involving malignancy or increased angiogenesis, wherein R<SUB>1</SUB>-R<SUB>11</SUB>, X, Y, Z, and n are as defined herein.
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| 申请公布号 |
US2006247448(A1) |
申请公布日期 |
2006.11.02 |
| 申请号 |
US20040507067 |
申请日期 |
2004.11.10 |
| 申请人 |
EISAI CO., LTD. |
发明人 |
BOIVIN ROCH;CHIBA KENICHI;CHOW JESSE;DU HONG;EGUCHI YOSHIHITO;FUJITA MASANORI;GOTO MASAKI;GUSOVSKY FABIAN;HARMANAGE JEAN-CHRISTOPHE;INOUE ATSUSHI;JIANG YIMIN;KAWADA MEGUMI;KAWAI TAKATOSHI;KAWAKAMI YOSHIYUKI;KIMURA AKIFUMI;KOTAKE MAKOTO;KUBOI YOSHIKAZU;LEMELIN CHARLES-ANDRE;LI XIANG-YI;MATSUSHIMA TOMOHIRO;MIZUI YOSHIHARU;MURAMOTO KENZO;SAKURAI HIDEKI;SHEN YONG-CHUN;SHIROTA HIROSHI;SPYVEE MARK;TANAKA ISAO;WANG JOHN (.;YAMAMOTO SATOSHI;YONEDA NAOKI |
| 分类号 |
C07D313/08;C07D491/044;A61K31/335;A61K31/36;A61K31/365;A61K31/395;A61K31/4178;A61K31/4188;A61K31/5377;A61P1/00;A61P1/04;A61P1/16;A61P3/10;A61P7/04;A61P9/00;A61P9/10;A61P11/00;A61P11/02;A61P11/06;A61P17/00;A61P17/04;A61P17/06;A61P17/16;A61P19/02;A61P19/04;A61P19/10;A61P21/04;A61P25/00;A61P25/02;A61P25/08;A61P25/28;A61P27/02;A61P29/00;A61P31/04;A61P31/18;A61P33/06;A61P35/00;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07D267/00;C07D313/00;C07D401/12;C07D405/12;C07D491/04;C07D493/04;C07D521/00 |
主分类号 |
C07D313/08 |
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