发明名称 |
PREVENTIVE OR REMEDY FOR BOWEL DISEASE |
摘要 |
It is intended to provide a preventive or a remedy for inflammatory colitis, irritable bowel syndrome and various diarrhea caused by other factors. It was found for the first time that CRAC/SOC channel plays a physiologically important role in water secretion or absorption in gastrointestinal epithelial cells and a CRAC/SOC channel inhibitor is useful for preventing and treating diarrhea caused by various factors, and a preventive and a remedy for diarrhea comprising a compound inhibiting the calcium release activated calcium channel as an active ingredient, particularly a remedy for diarrheal symptoms associated with inflammatory bowel diseases and a remedy for irritable bowel syndrome are provided. |
申请公布号 |
WO2006115140(A1) |
申请公布日期 |
2006.11.02 |
申请号 |
WO2006JP308185 |
申请日期 |
2006.04.19 |
申请人 |
ASTELLAS PHARMA INC.;ISHIKAWA, JUN;TAKEZAWA, RYUICHI;MASUNAGA, YOUHEI |
发明人 |
ISHIKAWA, JUN;TAKEZAWA, RYUICHI;MASUNAGA, YOUHEI |
分类号 |
A61K45/00;A61K31/4439;A61P1/04;A61P1/12;C07D401/12 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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