METHOD FOR EVALUATING COMPOUND USING BARLP AND SUBSTANCE FOR SUPPRESSING EATING AND BODY WEIGHT
摘要
<p>It is intended to provide a method for evaluating a compound which regulates eating or body weight characterized by comprising the steps of introducing a BARLP gene and preparing a cell expressing BARLP; bringing a test compound into contact with the cell; and detecting a specific binding of the test compound to the BARLP and a method for evaluating a compound further comprising the step of evaluating a test compound using a nonhuman genetically-engineered animal in which the BARLP gene is inactivated. According to this invention, knowledge about a relationship between BARLP and biological functions is obtained and a method for evaluating a compound targeting BARLP and a BARLP ligand obtained by the evaluation can be provided.</p>
申请公布号
WO2006115297(A1)
申请公布日期
2006.11.02
申请号
WO2006JP309122
申请日期
2006.04.25
申请人
BANYU PHARMACEUTICAL CO., LTD.;NAMBU, HIROHIDE;OZAKI, SATOSHI;TANAKA, TAKESHI;OHTA, HISASHI