发明名称 |
METHOD FOR EVALUATING COMPOUND USING BARLP AND SUBSTANCE FOR SUPPRESSING EATING AND BODY WEIGHT |
摘要 |
It is intended to provide a method for evaluating a compound which regulates eating or body weight characterized by comprising the steps of introducing a BARLP gene and preparing a cell expressing BARLP; bringing a test compound into contact with the cell; and detecting a specific binding of the test compound to the BARLP and a method for evaluating a compound further comprising the step of evaluating a test compound using a nonhuman genetically- engineered animal in which the BARLP gene is inactivated. According to this invention, knowledge about a relationship between BARLP and biological functions is obtained and a method for evaluating a compound targeting BARLP and a BARLP ligand obtained by the evaluation can be provided.
|
申请公布号 |
CA2606083(A1) |
申请公布日期 |
2006.11.02 |
申请号 |
CA20062606083 |
申请日期 |
2006.04.25 |
申请人 |
BANYU PHARMACEUTICAL CO., LTD. |
发明人 |
OHTA, HISASHI;TANAKA, TAKESHI;NAMBU, HIROHIDE;OZAKI, SATOSHI |
分类号 |
C12Q1/02;A61K45/00;A61P3/04;C12N15/09;C12Q1/68 |
主分类号 |
C12Q1/02 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|