发明名称 |
Methods of synthesizing 3-amino-1,2,4-benzotriazines |
摘要 |
An improved method of producing 3-amino-1,2,4-benzotriazines using nitrobenzene or a derivative thereof, a guanidine salt and a base as reactants is provided. The method is carried out at a moderate reaction temperature without producing halide wastes derived from nucleophilic substitution and acid byproducts.
|
申请公布号 |
US7129349(B2) |
申请公布日期 |
2006.10.31 |
申请号 |
US20050528090 |
申请日期 |
2005.09.22 |
申请人 |
TRUSTEES OF DARTMOUTH COLLEGE |
发明人 |
MOSKALEV NIKOLAI V.;GRIBBLE GORDON W. |
分类号 |
C07D253/10;A61K31/53;A61P31/04;A61P33/06;A61P35/00;C07D253/065;G01N |
主分类号 |
C07D253/10 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|