发明名称 Methods of synthesizing 3-amino-1,2,4-benzotriazines
摘要 An improved method of producing 3-amino-1,2,4-benzotriazines using nitrobenzene or a derivative thereof, a guanidine salt and a base as reactants is provided. The method is carried out at a moderate reaction temperature without producing halide wastes derived from nucleophilic substitution and acid byproducts.
申请公布号 US7129349(B2) 申请公布日期 2006.10.31
申请号 US20050528090 申请日期 2005.09.22
申请人 TRUSTEES OF DARTMOUTH COLLEGE 发明人 MOSKALEV NIKOLAI V.;GRIBBLE GORDON W.
分类号 C07D253/10;A61K31/53;A61P31/04;A61P33/06;A61P35/00;C07D253/065;G01N 主分类号 C07D253/10
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