发明名称 A PYRIDINE-N-OXIDE DERIVATIVE, AND PROCESS FOR ITS TRANSFORMATION INTO PHARMACEUTICALLY EFFECTIVE COMPOUNDS
摘要 <p>The invention relates to N-[2-hydroxy-3-(1-piperidinyl)-propoxy]-pyridine-1-oxide-3-carboxamidine and its optically active enantiomers. (R)-(-)-N-[2-hydroxy-3-(1-piperidinyl)-propoxy]-pyridine-1-oxide-3-carboxamidine and (S)-(+)-N-[2-hydroxy-3-(1-piperidinyl)-propoxy]-pyridine-1-oxide-3-carboxamidine. Furthermore, the invention relates to the preparation of N-[2-hydroxy-3-(1-piperidinyl)-propoxy]-pyridine-1-oxide-3-carboxyimidoyl chloride, which may be used as an active ingredient of medicaments, and the preparation of the optically active enantiomers of this compound using the compounds of the invention as intermediate substances.</p>
申请公布号 SI1274685(T1) 申请公布日期 2006.10.31
申请号 SI20010030607T 申请日期 2001.04.17
申请人 CYTRX CORPORATION 发明人 RIGDI LSSZLO;JEGESNE CSAKAI ZITA;GRUBER LAJOS;ITVIS LSSZLO;TOTH JUZSEF;TIMISKIZI ISTVSN;SZAKACSNE SCHMIDT ANIKU;REIDER FERENCNU;SCHNEIDERNE BARLAY MSRIA
分类号 C07B57/00;C07D213/89 主分类号 C07B57/00
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