发明名称 |
Pathological tissue detection and treatment employing targeted benzoindole optical agents |
摘要 |
Novel tumor specific phototherapeutic and photodiagnostic agents are disclosed. The compounds consist of a carbocyanine dye for visualization, photosensitizer for photodynamic treatment, and tumor receptor-avid peptide for site-specific delivery of the probe and phototoxic agent to diseased tissues. A combination of these elements takes full advantage of the unique and efficient properties of each component for an effective patient care management.
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申请公布号 |
US7128896(B2) |
申请公布日期 |
2006.10.31 |
申请号 |
US20040847121 |
申请日期 |
2004.05.17 |
申请人 |
MALLINCKRODT INC. |
发明人 |
ACHILEFU SAMUEL;DORSHOW RICHARD B.;RAJAGOPALAN RAGHAVAN;BUGAJ JOSEPH E. |
分类号 |
A61B10/00;A61K38/00;A61B5/00;A61B8/00;A61K41/00;A61K49/00;A61P9/10;A61P35/00;A61P35/04;C07D209/60;C07D417/04;C07D417/14;C07K7/04;C09B23/08 |
主分类号 |
A61B10/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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