Microbiological processes for the production of 7 alpha-substituted 11 alpha-hydroxy steroids

摘要

Disclosed is a microbiological process for the production of 7-alpha-substituted 11-alpha-hydroxy steroids of formula 4,B, wherein 7-alpha-substituted steroids of formula D are hydroxylated with the use of a microorganism selected from Beauveria sp., Curvularia sp., Gibberella sp., Glomerella sp., Gnomonia sp., Haplosporella sp., Helicostylum sp., Nigrospora sp., and Syncephalastrum sp.