| 摘要 |
Described are prognostic methods which are useful in medicine, particularly cancer chemotherapy. The object is to provide a method for assessing GST-pi expression levels in fixed or fixed and paraffin embedded tissues and prognosticate the probable resistance or sensitivity of a patient's tumour to treatment with platinum-based therapies by examination of the amount of GST-pi mRNA in a patient's tumour cells and comparing it with a predetermined threshold expression level. More specifically, described are oligonucleotide primer pairs for GST-pi and methods comprising their use for detecting levels of GST-pi mRNA.
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