发明名称 A METHOD FOR DETERMINING THE BIOLOGICAL ACTIVITY OF DEFIBROTIDE
摘要 An enzymatic method for determining the biological activity of defibrotide is described. The method, which is based on the capacity of defibrotide to potentiate the enzymatic activity of plasmin, comprises the steps of: a) bringing into contact defibrotide, plasmin and a substrate specific for the plasmin which, by reaction with the plasmin, provides a measurable product and b) measuring the amount of product formed at successive times.
申请公布号 RS63104(A) 申请公布日期 2006.10.27
申请号 YU2004P000631 申请日期 2002.11.27
申请人 GENTIUM SPA 发明人 PORTA ROBERTO;CATTANEO FRANCO;FERRO LAURA
分类号 C12Q1/37;C12Q1/56;C12Q1/68;G01N33/48;(IPC1-7):C12Q1/37 主分类号 C12Q1/37
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