发明名称 C-17 SPIROLACTONIZATION AND 6,7 OXIDATION OF STEROIDS
摘要 Novel processes for the C-17 spirolactonization and 6,7 oxidation of steroid compounds are provided. In certain preferred embodiments, the present invention provides for the preparation of steroid compounds which are useful in the preparation of methyl hydrogen 9,11?-epoxy-17?-hydroxy-3-oxopregn-4-ene-7?, 21-dicarboxylate, -lactone (otherwise referred to as eplerenone or epoxymexrenone).
申请公布号 RS90504(A) 申请公布日期 2006.10.27
申请号 YU2004P000905 申请日期 2003.03.21
申请人 PHARMACIA CORPORATION 发明人 PEARLMAN BRUCE ALLEN;PADILLA AMPHLETT GREG;HAVENS JEFFREY;MACKEY SONJA;WU HAIFENG;MILLER PAULA;POZZO MARK;CHOU SHINE
分类号 C07J21/00;C07C41/50;C07C43/305;C07J1/00;C07J71/00;(IPC1-7):C07J1/00 主分类号 C07J21/00
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