发明名称 Reduction of gelatin cross-linking in the gelatin shell of gelatin capsules by incorporating a free amino acid into the capsule shall and a carboxylic acid ester into the capsule filling
摘要 Described are compositions and methods for reducing cross-linking in the gelatin shell of gelatin capsules by incorporation of a free amino acid into the capsule shell and by inclusion of an ester of carboxylic acid either into the capsule filling, and/or into the capsule shell and/or into the lubrication agent, or in combinations thereof. Also described are soft gelatin capsules characterised by improved stability as compared with gelatin capsules that do not contain amino acid in the shell and carboxylic acid ester in the filling, shell or in the lubrication agent, or in combinations thereof.
申请公布号 NZ537022(A) 申请公布日期 2006.10.27
申请号 NZ20030537022 申请日期 2003.06.05
申请人 IVAX PHARMACEUTICALS S 发明人 VRANA, ALES
分类号 A61K9/48;A61K9/64;(IPC1-7):A61K9/48 主分类号 A61K9/48
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