发明名称 DERIVATIVES OF 5-(PYRIDIN-3-YL)-1-AZABICYCLO(3.2.1)OCTANE, THE PREPARATION THEREOF AND THE APPLICATION OF SAME IN THERAPEUTICS
摘要 The invention relates to compounds having general formula (I), wherein R denotes a halogen atom, a phenyl group which is substituted by one or more groups selected from among halogen atoms and the (Cl-C6) alkyl, (C1-C6) alcoxy, nitro, amino, trifluoromethyl, cyano, hydroxy, acetyl or methylenedioxy groups, a pyridinyl group, a thienyl group, a indolyl group, or a pyrimidinyl group which is optionally substituted by one or more (C1-C6) alcoxy groups. Moreover, among the two carbon-carbon bonds denoted by ----, one is simple and the other can be simple or double. The inventive compounds are nicotinic receptor ligands.
申请公布号 RS59904(A) 申请公布日期 2006.10.27
申请号 YU2004P000599 申请日期 2003.01.03
申请人 SANOFI-AVENTIS 发明人 GALLI FREDDERIC;LECLERC ODILE;LOCHEAD ALISTAIR;NEDELEC ALAIN
分类号 A61K31/437;A61K31/439;A61K31/444;A61K31/4545;A61K31/46;A61K31/4709;A61K31/506;A61K31/5377;A61K31/55;A61P25/00;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P25/30;C07D;C07D209/00;C07D221/00;C07D471/08;C07D471/18;(IPC1-7):C07D471/06 主分类号 A61K31/437
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