FUNCTIONS AND USES OF GPR39 GENE IN MAMMALIAN CENTRAL NERVOUS SYSTEM

摘要

The present invention provides mammalian GPR39 gene, its coded products, and the uses in regulating appetite and sense of pain. A pharmaceutical composition and a health product comprising GPR39 protein are also provided. The health product and the pharmaceutical composition for the inhibition of appetite or sense of pain comprise safe and efficient amount of antagonists of mammalian GPR39 protein (for example 0.01-99%) and bromatologically or pharmaceutically acceptable carriers (for example 1-99.99wt%).