| 摘要 |
Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. These novel compounds have the structure: (I) or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein G, L, Q, Z, R<SUB>6</SUB>, R<SUB>7</SUB>, and R<SUB>8</SUB> are defined herein. |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY;LI, JAMES, J.;HAMANN, LAWRENCE, G.;RUAN, ZHEMING;COOPER, CHRISTOPHER, B.;WU, SHUNG, C.;SIMPKINS, LIGAYA, M.;WANG, HAIXIA;NAYEEM, AKBAR;KRYSTEK, STANLEY, R., JR. |
发明人 |
LI, JAMES, J.;HAMANN, LAWRENCE, G.;RUAN, ZHEMING;COOPER, CHRISTOPHER, B.;WU, SHUNG, C.;SIMPKINS, LIGAYA, M.;WANG, HAIXIA;NAYEEM, AKBAR;KRYSTEK, STANLEY, R., JR. |
