PREPARATION OF SEVOFLURANE WITH NEGLIGIBLE WATER CONTENT
摘要
Provided is a sevoflurane anesthetic product which can remain substantially undegraded after long periods of storage, as well as a method for preparing the product. The product comprises sevoflurane in a glass container having a water content of less than 130 ppm. The method comprises drying sevoflurane having a water content of greater than 130 ppm to a water content les than 130 ppm. A preferred method of drying comprises contacting a sevoflurane composition having a water content of greater than 130 ppm with alumina-containing molecular sieves such that the water content is reduced to less than 130 ppm.
申请公布号
WO2006113636(A2)
申请公布日期
2006.10.26
申请号
WO2006US14427
申请日期
2006.04.18
申请人
MINRAD INC.
发明人
TERRELL, ROSS, C.;LEVINSON, JOSHUA, A.;MCNEIRNEY, JOHN, C.