USE OF MAGNETIC MATERIAL TO DIRECT ISOLATION OF COMPOUNDS AND FRACTIONATION OF MULTIPART SAMPLES
摘要
Methods for isolating a compound from a multipart, typically biological sample. The methods use at least one paramagnetic particle having an associated electronic charge to bind compounds with the opposite charge to form a particle/compound complex. Alternatively, the paramagnetic particles have a ligand or functional group with an affinity for a target compound to form a particle/compound complex. The complex can be immobilized by applying a magnetic field to the particle/protein complex. The sample may be further processed to obtain a protein sample in a more pure form or a sample depleted of select compounds.
申请公布号
WO2006017428(A3)
申请公布日期
2006.10.26
申请号
WO2005US27209
申请日期
2005.08.01
申请人
BECTON, DICKINSON AND COMPANY;FORT, THOMAS, L.;COLLIS, MATTHEW, P.;GENTLE, JR., THOMAS, M.
发明人
FORT, THOMAS, L.;COLLIS, MATTHEW, P.;GENTLE, JR., THOMAS, M.