发明名称 |
Dendritic cell co-stimulatory molecules |
摘要 |
A novel costimulatory protein molecule, B7-DC, which is a member of the B7 family, is described as is DNA coding therefor and expression vectors comprising this DNA. B7-DC protein, fragments, fusion polypeptides/proteins and other functional derivatives, and transformed cells expressing B7-DC are useful in vaccine compositions and methods. Compositions and methods are disclosed for inducing potent T cell mediated responses that can be harnessed for anti-tumor and anti-viral immunity. |
申请公布号 |
AU2001255700(C1) |
申请公布日期 |
2006.10.26 |
申请号 |
AU20010255700 |
申请日期 |
2001.04.27 |
申请人 |
THE JOHNS HOPKINS UNIVERSITY |
发明人 |
KEVIN S. GORSKI;DREW M. PARDOLL;SU-YI TSENG;HARUO TSUCHIYA |
分类号 |
C12N15/09;C12N15/12;A61K35/12;A61K35/14;A61K35/76;A61K38/00;A61K39/39;A61K39/395;A61K48/00;A61P35/00;A61P37/04;A61P37/06;C07K14/705;C07K14/725;C07K16/28;C07K19/00;C12N5/10;C12P21/08 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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