发明名称 |
METHOD FOR MEASURING ION CHANNEL ACTIVITY |
摘要 |
The present invention discloses a human embryo kidney cell or cell line transfected with a GABA-gated chloride channel derived from an insect of the order of Lepidoptera, Diptera, Coleoptera, Homoptera, Acarina, Thysanaptera, Heteroptera, Hymenoptera or Isoptera and its use in a one-pot, high-throughput method for the measurement of the change in membrane potential in a cell or cell line. The method is particularly effective in measuring changes in membrane potential resulting from a compound acting on a GABA-gated chloride channel derived from a tobacco budworm. |
申请公布号 |
WO03093789(A3) |
申请公布日期 |
2006.10.26 |
申请号 |
WO2003US13170 |
申请日期 |
2003.04.30 |
申请人 |
FMC CORPORATION;CHEN, RUIHUA;KINNE, LYLE, P.;WRZESINSKI, AMY;ALLENZA, PAUL |
发明人 |
CHEN, RUIHUA;KINNE, LYLE, P.;WRZESINSKI, AMY;ALLENZA, PAUL |
分类号 |
C12N5/06;G01N33/15;C12N5/10;C12N15/09;C12Q1/02;G01N33/50;G01N33/68;G01N33/94 |
主分类号 |
C12N5/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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