发明名称 |
STEM-LIKE CELLS IN BONE SARCOMAS |
摘要 |
<p>Isolation and purification of stem cells from within a bulk sarcoma tumor. These cells express the marker genes of pluripotent embryonic stem cells, Stat 3, Oct 3/4, and Nanog. A subset of these cells show the surface marker of mesenchymal stem cells Stro-1, as well as express attributes of mesodermal, ectodermal, and endodermal differentiation. The isolation, purification and characterization of these stem cells now provides the ideal target for the development of highly effective therapies against tumors.</p> |
申请公布号 |
WO2006113181(A2) |
申请公布日期 |
2006.10.26 |
申请号 |
WO2006US13092 |
申请日期 |
2006.04.07 |
申请人 |
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.;GIBBS, JR., CHARLES PARKER;STEINDLER, DENNIS |
发明人 |
GIBBS, JR., CHARLES PARKER;STEINDLER, DENNIS |
分类号 |
C12N5/0735 |
主分类号 |
C12N5/0735 |
代理机构 |
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代理人 |
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地址 |
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