5'/3' RATIOING PROCEDURE FOR DETECTION OF GENE REARRANGEMENTS

摘要

The present invention relates to methods and kits useful for the detection of gene rearrangements and the diagnosis of a propensity to develop a disease condition caused by the gene rearrangements, wherein two PCR products are prepared from the 5' side and from the 3' side of a putative breakpoint of the gene of interest, and the ratio of the two products are measured.