METHODS AND COMPOSITIONS FOR ENZYME-SPECIFIC ACTIVATION OF CARBOHYDRATE-CONJUGATED PRODRUGS
摘要
Methods for the targeted activation of prodrugs by enzymes, which cleave a linkage between a carbohydrate conjugate and a drug. Means to target the activation of prodrugs to specific cells by linking the enzyme to an antibody molecule. Carbohydrate conjugates of geldanamycin.
申请公布号
WO2006042056(A3)
申请公布日期
2006.10.26
申请号
WO2005US36061
申请日期
2005.10.07
申请人
THE OHIO STATE UNIVERSITY;SUN, DUXIN;WANG, PENG, GEORGE;MARTIN, EDWARD, JR.
