DIAGNOSTIC AND THERAPEUTIC POTENTIAL OF IMMUNE GLOBULIN INTRAVENOUS (IGIV) PRODUCTS
摘要
<p>The present invention provides IGIV and IGIV enriched for binding to amyloid fibrils and to partially denatured amyloidogenic precursor polypeptides. The present invention also provides methods for obtaining IGIV enriched for binding to amyloid fibrils and to partially denatured amyloidogenic precursor polypeptides. The IGIV recognizes amyloid fibrils and partially denatured amyloidogenic precursor polypeptides. They are useful for treating diseases and conditions associated with amyloid deposition. The IGIV of the present invention also are useful for diagnosing and detecting amyloid deposition.</p>
申请公布号
WO2006113347(A2)
申请公布日期
2006.10.26
申请号
WO2006US13858
申请日期
2006.04.13
申请人
THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION;O'NUALLAIN, BRIAN;HRNCIC, RUDI;WALL, JONATHAN, S.;SOLOMON, ALAN
发明人
O'NUALLAIN, BRIAN;HRNCIC, RUDI;WALL, JONATHAN, S.;SOLOMON, ALAN
