| 发明名称 |
Process for the preparation of Donepezil |
| 摘要 |
<p>The invention provides a process for the preparation of a compound of the formula 6 comprising the hydrolysis and decarboxylation of a compound of the formula 5 according to the reaction: <CHEM> wherein R and R2 are independently a C1-C4 alkyl group or an aralkyl group.</p> |
| 申请公布号 |
EP1386607(B1) |
申请公布日期 |
2006.10.25 |
| 申请号 |
EP20030253336 |
申请日期 |
2003.05.28 |
| 申请人 |
CHEMAGIS LTD. |
发明人 |
KASPI, JOSEPH;LERMAN, ORI;ARAD, ODED;ALNABARI, MOHAMMED;SERY, YANA |
| 分类号 |
A61K31/445;A61P25/28;C07D211/32;C07D211/34 |
主分类号 |
A61K31/445 |
| 代理机构 |
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