发明名称 Nucleic acid encoding a polypeptide promoting type II collagen formation and aggrecan production
摘要 A novel polypeptide, a polynucleotide encoding this polypeptide, an expression vector comprising this polynucleotide, a cell transfected with the expression vector, and a pharmaceutical composition for promoting type II collagen production, a pharmaceutical composition for promoting aggrecan production, and a pharmaceutical composition for treating and/or preventing osteoarthritis comprising the above polypeptide as an active ingredient are disclosed. The polypeptide exhibits an activity of promoting type II collagen production and/or an activity of promoting aggrecan production.
申请公布号 US7125715(B2) 申请公布日期 2006.10.24
申请号 US20020240535 申请日期 2002.10.02
申请人 ASTELLAS PHARMA INC. 发明人 YASUNAGA KUNIO
分类号 C12N5/00;A61K38/00;A61P19/02;A61P43/00;C07H21/04;C07K14/47;C12N1/14;C12N1/20;C12N9/64;C12N15/00;C12P21/08 主分类号 C12N5/00
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