| 摘要 |
Synthetic peptides for treatment of dental implant surfaces are provided to enhance adhesive activity of synthetic peptide with dental implant surface, and reduce the osseointegration period by stably inducing growth of bone. The synthetic peptides for treatment of dental implant surfaces represented by the formula: R1-(A-B-C)n-R2-(A-B-C)m-L are provided, wherein R1 is H, amino acid residue, fatty acid residue or copolymer main chain having biodegradable properties; R2 is a spacer; L is a link group selected from -OH, -NH2 and -COOH; A is an amino acid selected from Arg, Gly and Asp; B is an amino acid selected from Phe, Tyr and Trp; C is an amino acid selected from Leu, Ile and Val; and the copolymer main chain is a copolymer of polylactide and carboxylic acid.
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