发明名称 Upstream control elements of the proopiomelanocortin gene and their use
摘要 The nucleic acid sequence of the POMC enhancer is disclosed herein. Sequences from the human, rat, rabbit, hamster, mouse, and cow POMC enhancer are disclosed. Hybrid transgenes, comprising a POMC transcriptional control element operably linked to a nucleic acid sequence encoding a marker are also enclosed. In addition, transgenic mice carrying a hybrid transgene including a POMC control element operably linked to a marker are disclosed herein.
申请公布号 US7125979(B2) 申请公布日期 2006.10.24
申请号 US20030336091 申请日期 2003.01.03
申请人 OREGON HEALTH & SCIENCE UNIVERSITY 发明人 LOW MALCOLM J.;RUBINSTEIN MARCELO;JUNQUEIRA DE SOUZA FLAVIO SILVA
分类号 C07H21/04;G01N33/50;A01K67/027;A61K38/00;A61K38/22;A61K45/00;A61P1/14;A61P3/04;A61P7/00;A61P43/00;C07K14/665;C07K14/72;C12N5/06;C12N9/64;C12N15/09;C12N15/85;C12P21/02;C12Q1/02;C12Q1/68;G01N21/78;G01N33/15 主分类号 C07H21/04
代理机构 代理人
主权项
地址