| 摘要 |
FIELD: medicinal and pharmaceutical industry. ^ SUBSTANCE: method involves mixing polyphepan with a binding agent, drying a mixture and tabletting. Lactose is used as a binding, slipping and lubricating agent. After mixing components the prepared mixture is granulated and wetted granules are fed for drying up to residual moisture value 8%, not above. After drying termination granules are milled to particles size less 3.0 mm and then crushed granules are fed for tabletting and tablets with weight 0.5 g (± 0.025 g) are made of the following composition, g: polyphepan (as measure for dry matter), 0.35-0.40, and lactose, the balance. Invention provides retaining the sorption activity of polyphepan and to simplify the process. ^ EFFECT: improved preparing method. ^ 1 ex |
