发明名称 |
Therapeutic vaccine targeted against P-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers |
摘要 |
The invention relates to conjugates comprising all or part of the amino acid sequences of at least one peptide derived from an extracellular loop of the P-170 protein. The peptide may be covalently attached to spacers which may be polyethyleneglycol (PEG), polyglycine, polylysine or any polymer chain suitable for human use and is coupled at its free end to a phospholipids, e.g., phosphatidylethanolamine or any other chemically suitable phospholipid.
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申请公布号 |
US2006233758(A1) |
申请公布日期 |
2006.10.19 |
申请号 |
US20050274885 |
申请日期 |
2005.11.16 |
申请人 |
TOSI PIERRE-FRANCOIS;MADOULET CLAUDIE;NICOLAU CLAUDE Y;HICKMAN DAVID T |
发明人 |
TOSI PIERRE-FRANCOIS;MADOULET CLAUDIE;NICOLAU CLAUDE Y.;HICKMAN DAVID T. |
分类号 |
A61K39/00;A61K9/127;A61K48/00;C07K16/30;C12N5/06;G01N33/574 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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