The invention includes a method of selecting a mammal having or suspected of having a tumor for treatment with an Eg5 inhibitor drug, the method comprising providing a biological sample from a subject having cancer and testing the biological sample for expression of any one of the genes listed in Tables 1, 2 and 5, or their gene products, thereby to predict an increased likelihood of response to the Eg5 inhibitor drug.
申请公布号
WO2006109086(A2)
申请公布日期
2006.10.19
申请号
WO2006GB01384
申请日期
2006.04.13
申请人
ASTRAZENECA AB;ASTRAZENECA UK LIMITED;RONCO, LUCIENNE;WEBSTER, KEVIN;YU, LIHUA;ZHANG, XIAOLIN