Antibodies specific for ungulate PrP

摘要

The present invention provides antibodies that specifically bind with a high degree of binding affinity to a native ungulate PrP^C and/or a denatured ungulate PrP^Sc, but not to a native ungulate PrP^Sc. Preferred antibodies find native bovine PrP^C and treated PrP^Sc but not native bovine PrP^Sc and can be used in an assay to determine if a sample is infected with infectious prions, i.e. PrP^Sc.