NEW TRICYCLIC ANGIOTENSIN II AGONISTS

摘要

There is provided compounds of Formula (I), wherein A, X<SUB>1</SUB>, X<SUB>2</SUB>, X<SUB>3</SUB>, X<SUB>4</SUB>, Y<SUB>1</SUB>, Y<SUB>2</SUB>, Y<SUB>3</SUB>, Y<SUB>4</SUB>, Z<SUB>1</SUB>, Z<SUB>2</SUB>, R<SUP>4</SUP> and R<SUP>5</SUP> have meanings given in the description, and pharmaceuticalfy-acceptable salts thereof, which compounds are useful as selective agonists of the AT2 receptor, and thus, in particular, in the treatment of inter alia gastrointestinal conditions, such as dyspepsia, IBS and MOF, and cardiovascular disorders.