METHOD FOR DATA REDUCTION AND CALIBRATION OF AN OCT-BASED BLOOD GLUCOSE MONITOR

摘要

The present invention relates to a method for estimating blood glucose level s using a noninvasive optical coherence tomography-(OCT-) based blood glucose monitor. An algorithm correlates OCT-based estimated blood glucose data with actual blood glucose data determined by invasive methods. OCT-based data is fit to the obtained blood glucose measurements to achieve the best correlation. Once the algorithm has generated sets of estimated blood glucos e levels, it may refine the number of sets by applying one or more mathematica l filters. The OCT-based blood glucose monitor is calibrated using an Intensit y Difference plot or the Pearson Product Moment Correlation method.